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Myalgia or muscle pain is a painful sensation evolving from muscle tissue. It is a symptom of many diseases . The most common cause of acute myalgia is the overuse of a muscle or group of muscles ; another likely cause is viral infection , especially when there has been no injury .
Malaise is a non-specific symptom and can be present in the slightest ailment, such as an emotion (causing fainting, a vasovagal response) or hunger (light hypoglycemia [2]), to the most serious conditions (cancer, stroke, heart attack, internal bleeding, etc.).
The causes are many and can be divided into conditions that have true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. [citation needed]
Fixed muscle weakness is a static symptom as the muscle will be weak regardless of exercise or rest. [citation needed] A majority of patients with metabolic myopathies have dynamic rather than static findings, typically experiencing exercise intolerance, muscle pain, and cramps with exercise rather than fixed weakness. [38]
multi-joint pain without joint swelling or redness; headaches of a new type, pattern, or severity; unrefreshing sleep; post-exertional malaise lasting more than 24 hours. Final requirement. All other known causes of chronic fatigue must have been ruled out, specifically clinical depression, side effects of medication, eating disorders and ...
Inflammatory myopathy, also known as idiopathic inflammatory myopathy (IIM), is disease featuring muscle weakness, inflammation of muscles , and in some types, muscle pain . The cause of much inflammatory myopathy is unknown ( idiopathic ), and such cases are classified according to their symptoms and signs , electromyography , MRI , and ...
Post-exertional malaise (PEM) and exercise intolerance are common symptoms of post-acute infection syndromes. [5] Post-exertional malaise is a worsening of symptoms after minimal physical or mental activity, [6] and is a cardinal symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). [7]
Complex regional pain syndrome (CRPS Type 1 and Type 2), sometimes referred to by the hyponyms Reflex Sympathetic Dystrophy (RSD) or Reflex Neurovascular Dystrophy (RND), is a rare and severe form of neuroinflammatory and dysautonomic disorder causing chronic pain, neurovascular, and neuropathic symptoms.
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