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Erythroderma is an inflammatory skin disease with redness and scaling that affects nearly the entire cutaneous surface. [ 1 ] [ 2 ] This term applies when 90% or more of the skin is affected. In ICD-10 , a distinction is made between "exfoliative dermatitis" at L26, and "erythroderma" at L53.9.
Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
Those taking medication to manage existing mental health conditions may be more affected by heat as the side effects of some of these medications include changes in the regulation of body temperature. [72] Climate change also disrupts the conditions communities need for good mental health and wellbeing. This includes impacts to air quality ...
Generalized erythroderma – redness of the skin [3] Lymphadenopathy – swollen, enlarged lymph nodes [3] Atypical T cells – malignant lymphocytes known as "Sézary cells" seen in the peripheral blood with typical cerebriform nuclei (brain-shaped, convoluted nuclei) [8] [3] Hepatosplenomegaly– enlarged liver and spleen [9]
The scheme provides forms that allow members of the public to report suspected side effects, as well as health professionals. [6] NHS Digital publishes an information standard DCB1582 for electronic submission of adverse reactions by IT systems [7] (until 2014, this was ISB 1582 from the Information Standards Board). [8]
Ichthyosis bullosa of Siemens is an autosomal dominant genetic condition caused by a mutation in the gene for keratin 2e on chromosome 12. [4] [7] [8] [9]: 563 This means an affected person has a 50% chance of passing the condition on to their child.
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Most cases (approximately 75%) of collodion baby will go on to develop a type of autosomal recessive congenital ichthyosis (either lamellar ichthyosis or congenital ichthyosiform erythroderma). [5] In around 10% of cases the baby sheds this layer of skin and has normal skin for the rest of its life. [2] [5] This is known as self-healing ...