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5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]
[27] [28] However, 5-HTP has not been associated with cardiac toxicity in humans. [19] [18] [17] [29] It has been suggested that 5-HTP may cause eosinophilia-myalgia syndrome (EMS), a serious condition which results in extreme muscle tenderness, myalgia, and blood abnormalities. However, there is evidence to show that EMS was likely caused by a ...
While acute inflammation is the body’s natural response to injury or infection, chronic inflammation can lead to serious health issues like heart disease, arthritis and autoimmune disorders.
However, the tryptophan derivative 5-HTP (5-hydroxytryptophan), used in the treatment of depression, raises blood serotonin level considerably [citation needed]. It has yet to be reported to be associated with valve disease or other fibrosis, but for the previous theoretical reasons, it has been suggested as a possible danger. [citation needed]
“Acute inflammation helps to protect and heal our bodies, however, chronic inflammation is a prolonged state that can damage healthy cells, tissues, and organs contributing to various diseases ...
Experts explain the difference between acute and chronic inflammation, as well as medications and lifestyle changes that help reduce inflammation. 5 Signs You Have Inflammation in Your Body Skip ...
Myocarditis refers to an underlying process that causes inflammation and injury of the heart. It does not refer to inflammation of the heart as a consequence of some other insult. Many secondary causes, such as a heart attack, can lead to inflammation of the myocardium and therefore the diagnosis of myocarditis cannot be made by evidence of ...
[4] [5] Diagnosis is based on the presence of chest pain, a pericardial rub, specific electrocardiogram (ECG) changes, and fluid around the heart. [6] A heart attack may produce similar symptoms to pericarditis. [1] Treatment in most cases is with NSAIDs and possibly the anti-inflammatory medication colchicine. [6]