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Coronary artery disease is characterized by heart problems that result from atherosclerosis. [34] Atherosclerosis is a type of arteriosclerosis which is the "chronic inflammation of the arteries which causes them to harden and accumulate cholesterol plaques (atheromatous plaques) on the artery walls". [35]
Arterial stiffness occurs as a consequence of biological aging, arteriosclerosis and genetic disorders, such as Marfan, Williams, and Ehlers-Danlos syndromes. [1] Inflammation plays a major role in arteriosclerosis and arterial stiffness. [2]
If reversed, coma, persistent vegetative state, post-cardiac arrest syndrome; if not reversed, death: Usual onset: The risk of onset increases with age [3] Causes: Coronary artery disease, congenital heart defect, major blood loss, lack of oxygen, electrical injury, very low potassium, heart failure, myocardial infarction: Diagnostic method
Coronary ischemia can have serious consequences if it is not treated. Plaques in the walls of the coronary arteries can rupture, resulting in occlusion of the artery and deprivation of blood flow and oxygen to the heart muscle, resulting in cardiac cell death. [9] This is known as myocardial infarction. [9]
When atherosclerosis has become severe and caused irreversible ischemia, such as tissue loss in the case of peripheral artery disease, surgery may be indicated. Vascular bypass surgery can re-establish flow around the diseased segment of the artery, and angioplasty with or without stenting can reopen narrowed arteries and improve blood flow.
Symptoms include chest pain or angina, shortness of breath, and fatigue. [6]A completely blocked coronary artery will cause a heart attack. [6] Common heart attack symptoms include chest pain or angina, pain or discomfort that spreads to the shoulder, arm, back, neck jaw, teeth or the upper belly, cold sweats, fatigue, heartburn, nausea, shortness of breath, or lightheadedness.
Echocardiography can quantify heart functioning by measuring, for example, enlargement of the left ventricle, the ejection fraction, and the situation of the heart valves. The most accurate ways to detect CAD are the coronary angiogram and the coronary CT angiography. [4] An angiogram can provide detailed anatomy of coronary circulation and ...
Acute coronary syndrome (ACS) is a syndrome due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function properly or dies. [1] The most common symptom is centrally located pressure-like chest pain , often radiating to the left shoulder [ 2 ] or angle of the jaw, and associated with nausea and ...
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