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Phineas P. Gage (1823–1860) was an American railroad construction foreman remembered for his improbable: 19 survival of an accident in which a large iron rod was driven completely through his head, destroying much of his brain's left frontal lobe, and for that injury's reported effects on his personality and behavior over the remaining 12 years of his life—effects sufficiently ...
Connectograms have been used to monitor the progression of neurological recovery of patients who suffered a traumatic brain injury (TBI). [12] They have also been applied to famous patient Phineas Gage, to estimate damage to his neural network (as well as the damage at the cortical level—the primary focus of earlier studies on Gage). [13]
White matter fiber connections in DTI data are then drawn between these cortical regions and weighted by fractional anisotropy and strength of the connection. Such graphs have even been used to analyze the damage done to the famous traumatic brain injury patient Phineas Gage. [56]
Phineas Gage, who sustained a severe frontal lobe injury in 1848, has been called a case of dysexecutive syndrome. Gage's psychological changes are almost always exaggerated – of the symptoms listed, the only ones Gage can be said to have exhibited are "anger and frustration", slight memory impairment, and "difficulty in planning". [21]
Diffuse axonal injury is caused by shearing forces on the brain leading to lesions in the white matter tracts of the brain. [31] These shearing forces are seen in cases where the brain had a sharp rotational acceleration, and is caused by the difference in density between white matter and grey matter. [32]
This personality change is characteristic of damage to the frontal lobe, and was exemplified in the case of Phineas Gage. The frontal lobe is the same part of the brain that is responsible for executive functions such as planning for the future, judgment, decision-making skills, attention span, and inhibition. These functions can decrease ...
A penetrating head injury, or open head injury, is a head injury in which the dura mater, the outer layer of the meninges, is breached. [1] Penetrating injury can be caused by high-velocity projectiles or objects of lower velocity such as knives, or bone fragments from a skull fracture that are driven into the brain.
Phineas Gage's case of traumatic brain injury that greatly stimulated discussion on brain function and physiology Henry Molaison , formerly known as patient H.M., underwent neurosurgery to remove scar tissue in his brain that was causing debilitating epileptic seizures , neurosurgeon William Beecher Scoville performed the surgery which created ...