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Digital pathology is a sub-field of pathology that focuses on managing and analyzing information generated from digitized specimen slides. It utilizes computer-based technology and virtual microscopy to view, manage, share, and analyze digital slides on computer monitors. [ 1 ]
The Digital Pathology Association (DPA), is a non-profit organization of professionals in the field of pathology and related technologies. It has over 2,000 members and is headquartered in Carmel, Indiana .
Major topics of pathology informatics, including some that underlie telepathology: slide scanning, digital imaging and networks. Telepathology is the practice of pathology at a distance. It uses telecommunications technology to facilitate the transfer of image-rich pathology data between distant locations for the purposes of diagnosis ...
CellNetix spent 6 months validating WSI for use in diagnostic processes. It is now in daily use for digital IHC reads by pathologists at remote locations. They are also using WSI for HER2/neu diagnosis after a lengthy validation (comparing diagnosis by glass slide vs. digital image) for many cases by different pathologists. [5]
Major topics of pathology informatics, with major topics that underlie virtual microscopy, including slide scanning, digital imaging and networks.. Virtual microscopy is a method of posting microscope images on, and transmitting them over, computer networks.
Digital polymerase chain reaction (digital PCR, DigitalPCR, dPCR, or dePCR) is a biotechnological refinement of conventional polymerase chain reaction methods that can be used to directly quantify and clonally amplify nucleic acids strands including DNA, cDNA, or RNA.
The guideline consists of the following elements: 1) experimental design, 2) sample, 3) nucleic acid extraction, 4) reverse transcription, 5) qPCR target information, 6) oligonucleotides, 7) protocol, 8) validation, and 9) data analysis. Specific items within each element carry a label of either E (essential) or D (desirable).
Developing an understanding of clinical significance for specific biomarkers can be a difficult process. There are two steps of certification for a surrogate endpoint to be fully established: Qualification and Validation. For a biomarker to become qualified it must go through a somewhat formal qualification process.