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Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder. It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
Nocturnal enuresis (NE), also informally called bedwetting, is involuntary urination while asleep after the age at which bladder control usually begins. [1]
However currently only oxybutynin has an FDA-approved labeled indication in children aged 6 and older. [ 5 ] [ 34 ] An additional third-line alternative shown to be effective is the tricyclic antidepressant imipramine , however the use of tricyclic antidepressants carries the risk of cardiotoxicity and is not recommended to be given without ...
A number of medications exist to treat urinary incontinence including: fesoterodine, tolterodine and oxybutynin. [59] These medications work by relaxing smooth muscle in the bladder. [ 60 ] [ 61 ] [ 62 ] While some of these medications appear to have a small benefit, the risk of side effects are a concern. [ 59 ]
Tofranil – a tricyclic antidepressant used to treat depression, anxiety, agitation, panic disorder and bedwetting; Topamax – an anticonvulsant used to treat epilepsy and migraine headaches; Trileptal (oxcarbazepine) – an anticonvulsant used as a mood stabilizer
Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. [2] The frequent need to urinate may occur during the day, at night, or both. [4]
These are used for patients with over-active bladder muscles, who have lost the ability to hold their urine in. [2] Oxybutynin is a common anti-cholinergic medication used to reduce bladder contractions by blocking M3 muscarinic receptors in the detrusor muscle.
Diurnal enuresis is daytime wetting (functional daytime urinary incontinence).Nocturnal enuresis is nighttime wetting. Enuresis is defined as the involuntary voiding of urine beyond the age of anticipated control.
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