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Fluticasone Furoate falls under the drug class of Corticosteroid. Corticosteroids are a class of steroid hormones produced naturally by the adrenal cortex, which is located on top of the kidneys. They play a crucial role in regulating various physiological processes in the body, including metabolism, immune response, and inflammation.
Common side effects when inhaled include upper respiratory tract infections, sinusitis, thrush, and cough. [8] Common side effects when used in the nose include nosebleeding and sore throat. [ 9 ] Unlike fluticasone furoate , which is approved in children as young as two years of age when used for allergies, fluticasone propionate is only ...
The effects of topical corticosteroids are not immediate and must be used for at least a few days for noticeable relief. As-needed use is less effective than regular recommended use. [2] Flunisolide should not be used for nasal infections. It should not be continued if symptoms are not relieved after regular use for over two to three weeks. [3]
Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include: Oxymetazoline; Phenylephrine; Xylometazoline
Nasal budesonide inhalers have been associated with a number of side effects. [ 34 ] [ 35 ] These include nose irritation or burning, bleeding or sores in the nose, lightheadedness, upset stomach, cough, hoarseness, dry mouth, rash, sore throat, bad taste in mouth , change in mucus , and blurred vision. [ 36 ]
It is on the World Health Organization's List of Essential Medicines. [7] In 2022, it was the 25th most commonly prescribed medication in the United States, with more than 22 million prescriptions, [8] [9] although it is also sold over-the-counter (OTC). [10]
Common side effects when applied on the skin include acne, skin atrophy, and itchiness. [11] It works by decreasing inflammation. [10] Mometasone furoate was patented in 1981 and came into medical use in 1987. [14] It is on the World Health Organization's List of Essential Medicines [15] and is available as a generic medication.
Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)-dehydrogenation, 6α-, 9α-, 16α-, and 16β-substitution (with a halogen or methyl group), 16α,17α-acetonidation, and 17α- and 21-esterification.
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