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Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. [1] It is used to treat organophosphate poisoning [2] in conjunction with atropine and either diazepam or midazolam. It is a white solid.
Saruparib is a investigational new drug that is being evaluated for the treatment of cancer. [1] It first-in-class selective inhibitor of poly-ADP ribose polymerase 1 (PARP1), designed to treat cancers with homologous recombination repair (HRR) deficiencies as a result of mutations in BRCA1 , BRCA2 , PALB2 , RAD51C , or RAD51D genes.
Pyridine-3-carbaldehyde, also known as nicotinaldehyde, is an organic compound with the formula C 5 H 4 NCHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-2-carboxaldehyde and pyridine-4-carboxaldehyde. It is a colorless liquid that is routinely available commercially. It can be produced from nicotinonitrile ...
In 1989, 26,000 tonnes of pyridine was produced worldwide. Other major derivatives are 2-, 3-, 4-methylpyridines and 5-ethyl-2-methylpyridine. The combined scale of these alkylpyridines matches that of pyridine itself. [2] Among the largest 25 production sites for pyridine, eleven are located in Europe (as of 1999). [24]
98-98-6 59-67-6 55-22-1 All isomers share the molecular weight 123,11 g/mol and the chemical formula C 6 H 5 NO 2. See also. Pyridinedicarboxylic acid
Pyridine-2-carbaldehyde, also called 2-formylpyridine, is an organic compound with the formula NC 5 H 4 CHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-3-carboxaldehyde and pyridine-4-carboxaldehyde. Pyridine-2-carbaldehyde is a colorless oily liquid with a distinctive odor.
2-Methylpyridine, or 2-picoline, is the compound described with formula C 6 H 7 N. 2-Picoline is a colorless liquid that has an unpleasant odor similar to pyridine. It is mainly used to make vinylpyridine and the agrichemical nitrapyrin .
Picoline was obtained, in impure form, in 1826 by the German chemist Otto Unverdorben (1806 – 1873), who obtained it by the pyrolysis (roasting) of bones. [1] He called it Odorin due to its unpleasant smell. [2] In 1849, the Scottish chemist Thomas Anderson (1819 – 1874) prepared picoline in pure form, from coal tar and via the pyrolysis of ...