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Hydroxyapatite (IMA name: hydroxylapatite [5]) (Hap, HAp, or HA) is a naturally occurring mineral form of calcium apatite with the formula Ca 5 (PO 4) 3 (OH), often written Ca 10 (PO 4) 6 (OH) 2 to denote that the crystal unit cell comprises two entities. [6]
Salting out (also known as salt-induced precipitation, salt fractionation, anti-solvent crystallization, precipitation crystallization, or drowning out) [1] is a purification technique that utilizes the reduced solubility of certain molecules in a solution of very high ionic strength.
Apatite is a group of phosphate minerals, usually hydroxyapatite, fluorapatite and chlorapatite, with high concentrations of OH −, F − and Cl − ion, respectively, in the crystal. The formula of the admixture of the three most common endmembers is written as Ca 10 ( PO 4 ) 6 (OH,F,Cl) 2 , and the crystal unit cell formulae of the ...
It is a water-based salt solution containing disodium hydrogen phosphate, sodium chloride and, in some formulations, potassium chloride and potassium dihydrogen phosphate. The buffer helps to maintain a constant pH. The osmolarity and ion concentrations of the solutions are isotonic, meaning they match those of the human body.
Amorphous calcium phosphate (ACP) is a glassy solid that is formed from the chemical decomposition of a mixture of dissolved phosphate and calcium salts (e.g. (NH 4) 2 HPO 4 + Ca(NO 3) 2). The resulting amorphous mixture consists mostly of calcium and phosphate, but also contains varying amounts of water and hydrogen and hydroxide ions ...
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.
Tricalcium phosphate is produced commercially by treating hydroxyapatite with phosphoric acid and slaked lime. [4]It cannot be precipitated directly from aqueous solution. Typically double decomposition reactions are employed, involving a soluble phosphate and calcium salts, e.g. (NH 4) 2 HPO 4 + Ca(NO 3
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.