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Hepatic VOD is a dose-limiting toxicity. Symptoms of VOD include weight gain, elevated bilirubin, painful hepatomegaly, and edema. The reason busulfan causes VOD is mostly unknown and can be deadly. [4] Ursodiol may be considered for prophylaxis of veno-occlusive disease. Antiemetics are often administered prior to busulfan to prevent vomiting ...
Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria. It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus , from which its name derived. [ 8 ]
“Early outdoor time with a dose of vitamin D can improve mood and reduce stress-induced inflammation,” says Shapiro. The next time you pour yourself a cup of coffee, slide on a pair of ...
Medication is not always necessary or the best choice for treating a vision problem, and sometimes, medication isn't an option at all.But in many cases, it can certainly help with vision problems ...
Sandra Coto-Navarro, 48, is accused of killing 55-year-old Jose Portillo and hiding his body in her Queens, N.Y. apartment
Pre-exposure prophylaxis (PrEP), is the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent. Vaccination is the most commonly used form of pre-exposure prophylaxis ; other forms of pre-exposure prophylaxis generally involve drug treatment, known as chemoprophylaxis .
A Colorado woman pulled a page from an Alfred Hitchcock script, by killing her boyfriend for making fun of her with the help of a random man she’d met moments before on a bus, prosecutors said ...