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This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs.
Activation of gene transcription is a complex system of signal cascades and recruitment of necessary components such as RNA polymerase and transcription factors. IEGs are often the first responders to regulatory signals with many reaching peak expression within 30 minutes after stimuli compared to 2–4 hours in the case of delayed primary ...
MEF2, Myocyte Enhancer Factor 2, is a transcription factor with four specific numbers such as MEF2A, B, C, and D. Each MEF2 gene is located on a specific chromosome. MEF2 is known to be involved in the development and the looping of the heart (Chen) MEF2 is necessary for myocyte differentiation and gene activation (Black).
4211 17268 Ensembl ENSG00000143995 ENSMUSG00000020160 UniProt O00470 Q60954 RefSeq (mRNA) NM_002398 NM_001193271 NM_010789 RefSeq (protein) NP_002389 NP_001180200 NP_034919 Location (UCSC) Chr 2: 66.43 – 66.57 Mb Chr 11: 18.83 – 18.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene. Function Homeobox ...
PI3kinase. The pathophysiology of activated PI3K delta syndrome has several aspects. [2] The normal function has P110δ (PI3K) involved in immune system regulation. [9]P110δ effect is not limited to the immune system; P110δ has a presence in transformed epithelial cells and cell adhesion molecules (airway inflammation), and research has been done on the possibility of P110δ in the nervous ...
The mechanism of saRNA-mediated RNAa centers around the RNA-induced transcriptional activation (RITA) complex. [17] This complex includes: Argonaute 2 (AGO2): AGO2 binds to the guide strand of the saRNA and facilitates targeting to the gene promoter. AGO2 is the primary Argonaute protein involved in saRNA-mediated RNAa.
Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. [ 4 ] [ 5 ] MEF2C is a transcription factor in the Mef2 family.
Q-system is a genetic tool that allows to express transgenes in a living organism. [1] Originally the Q-system was developed [2] [3] for use in the vinegar fly Drosophila melanogaster, and was rapidly adapted for use in cultured mammalian cells, [2] zebrafish, [4] worms [5] and mosquitoes. [6]