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  2. Tryptophan - Wikipedia

    en.wikipedia.org/wiki/Tryptophan

    Tryptophan. Soluble in hot alcohol, alkali hydroxides; insoluble in chloroform. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Tryptophan (symbol Trp or W) [3] is an α- amino acid that is used in the biosynthesis of proteins.

  3. Tryptophan synthase - Wikipedia

    en.wikipedia.org/wiki/Tryptophan_synthase

    Tryptophan synthase or tryptophan synthetase is an enzyme (EC 4.2.1.20) that catalyzes the final two steps in the biosynthesis of tryptophan. [1][2] It is commonly found in Eubacteria, [3] Archaebacteria, [4] Protista, [5] Fungi, [6] and Plantae. [7] However, it is absent from Animalia. [8]

  4. 5-Hydroxytryptophan - Wikipedia

    en.wikipedia.org/wiki/5-Hydroxytryptophan

    5-Hydroxytryptophan (5-HTP), used medically as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin. 5-HTP can be manufactured and used as a drug and supplement with the INN oxitriptan. Brand names include Cincofarm, Levothym, Levotonine ...

  5. Tryptophan hydroxylase - Wikipedia

    en.wikipedia.org/wiki/Tryptophan_hydroxylase

    Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the monoamine neurotransmitter serotonin. Tyrosine hydroxylase , phenylalanine hydroxylase , and tryptophan hydroxylase together constitute the family of biopterin-dependent aromatic amino acid hydroxylases .

  6. trp operon - Wikipedia

    en.wikipedia.org/wiki/Trp_operon

    The trp operon is a group of genes that are transcribed together, encoding the enzymes that produce the amino acid tryptophan in bacteria. The trp operon was first characterized in Escherichia coli, and it has since been discovered in many other bacteria. [1] The operon is regulated so that, when tryptophan is present in the environment, the ...

  7. Tryptophan (data page) - Wikipedia

    en.wikipedia.org/wiki/Tryptophan_(data_page)

    The complete data for Tryptophan (. v. ) General information. Chemical formula: C11H12N2O2. Molar mass: 204.23 g·mol −1. Systematic name: ( S )-2-Amino-3- (1H-indol-3-yl)-propanoic acid. Abbreviations: W, Trp.

  8. Hypertryptophanemia - Wikipedia

    en.wikipedia.org/wiki/Hypertryptophanemia

    Hypertryptophanemia is a rare autosomal recessive [2] metabolic disorder that results in a massive buildup of the amino acid tryptophan in the blood, with associated symptoms and tryptophanuria (-uria denotes 'in the urine '). [3][4] Elevated levels of tryptophan are also seen in Hartnup disease, [5] a disorder of amino acid transport. [6]

  9. TPH2 - Wikipedia

    en.wikipedia.org/wiki/TPH2

    Tryptophan hydroxylase 2 (TPH2) is an isozyme of tryptophan hydroxylase found in vertebrates. In humans, TPH2 is primarily expressed in the serotonergic neurons of the brain, with the highest expression in the raphe nucleus of the midbrain. Until the discovery of TPH2 in 2003, [5] serotonin levels in the central nervous system were believed to ...

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