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About three per 100,000 people per year develop the systemic form. [3] The condition most often begins in middle age. [1] Women are more often affected than men. [1] Scleroderma symptoms were first described in 1753 by Carlo Curzio [9] and then well documented in 1842. [10] The term is from the Greek skleros meaning "hard" and derma meaning ...
[1] [2] Patients observe these symptoms and seek medical advice from healthcare professionals. Because most people are not diagnostically trained or knowledgeable, they typically describe their symptoms in layman's terms, rather than using specific medical terminology. This list is not exhaustive.
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).
Varies widely, often drug-induced [50] Interstitial cystitis: Bladder: Anti-urothelial and anti-nuclear antibodies Probable 100-450 per 100,000 women, less common in men [51] Primary sclerosing cholangitis: Bile ducts, can affect gallbladder: P-ANCA, Anti Smooth Muscle Antibodies (ASMA) Confirmed 1 per 100,000 [52]
Hereditary breast–ovarian cancer syndrome; Hereditary hyperbilirubinemia; Hereditary leiomyomatosis and renal cell cancer syndrome; Hereditary neuralgic amyotrophy; Hereditary nonpolyposis colorectal cancer; Hermansky–Pudlak syndrome; Hero syndrome; Heyde's syndrome; High-rise syndrome; HIV/AIDS; Holiday heart syndrome; Holt–Oram syndrome ...
In clinical trials, GLP-1 drug tirzepatide reduced sleep apnea events by as much as two-thirds over the course of 52 weeks in patients with obstructive sleep apnea. Patients taking a placebo ...
For example, a benign tumor of smooth muscle cells is called a leiomyoma (the common name of this frequently occurring benign tumor in the uterus is fibroid). Confusingly, some types of cancer use the -noma suffix, examples including melanoma and seminoma .