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U.S. Route 19E (US 19E) is a divided highway of US 19 in the U.S. states of North Carolina and Tennessee.The United States Numbered Highway, which is complemented by US 19W to the west, travels 75.9 miles (122.1 km) from US 19 and US 19W at Cane River, North Carolina, north to US 11E, US 19, and US 19W in Bluff City, Tennessee.
Bristol is located 20.95 miles east of Kingsport, Tennessee, 21.51 miles northeast of Johnson City, Tennessee, 38.74 miles northwest of Boone, North Carolina, 105.96 miles northeast of Knoxville, Tennessee, and 132.61 miles southwest of Roanoke, Virginia.
US 421 entering Tennessee from North Carolina US 421 enters Tennessee from North Carolina just north of Zionville, NC in Johnson County , concurrent with unsigned SR 34 , as a 2-lane highway. The highway then goes northwest to enter the oldest unincorporated community in the state, Trade , where it begins an unsigned concurrency with SR 67 .
Along its routing, US 421 serves several cities including Wilmington, North Carolina; Greensboro, North Carolina; Bristol, Tennessee and Virginia; Lexington, Kentucky; and Indianapolis, Indiana. US 421 is a spur route of US 21, which it meets west of Yadkinville, North Carolina.
U.S. Route 421 (US 421) is part of the United States Numbered Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana.In the U.S. state of North Carolina, US 421 travels 328 miles (528 km) from its southern terminus at Fort Fisher to the Tennessee state line near the community of Zionville, North Carolina.
The Tri-Cities is the region comprising the cities of Kingsport, Johnson City, and Bristol and the surrounding smaller towns and communities in Northeast Tennessee and Southwest Virginia. All three cities are located in Northeast Tennessee, while Bristol has a twin city of the same name in Virginia.
US 19 originally went from the North Carolina state line to US 511. In 1928, US 19 was extended with US 511 to Bristol and into Virginia. In 1930, US 19 south was truncated to Bluff City (the current State Route 44 [SR 44]/SR 390 junction), as US 19E was assigned to US 19 south to North Carolina.
Bristol, Johnson City, and Kingsport cooperated with Sullivan County to build an airport on 323 acres in Sullivan County, between the three cities. In September 1937, two small runways, a terminal building, and aircraft hangar had been built and the airport saw its first airliner, an American Airlines DC-2 .