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Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .
Rintatolimod, sold under the tradename Ampligen, is a medication intended for treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). [1] There is some evidence it may improve some ME/CFS symptoms. [1] It is an immunomodulatory double-stranded RNA drug similar to the prototypical RNA poly I:C.
The term post-infectious fatigue syndrome was initially proposed as a subset of "chronic fatigue syndrome" with a documented triggering infection, but might also be used as a synonym of ME/CFS or as a broader set of fatigue conditions after infection. [26] Many individuals with ME/CFS object to the term chronic fatigue syndrome. They consider ...
Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time, intended as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Most public health bodies, including the CDC and NICE, consider it ineffective, and its safety is disputed.
The CDC states that diagnostic tests should be directed to confirm or exclude other causes for fatigue and other symptoms. Further tests may be individually necessary to identify underlying or contributing conditions that require treatment. The following routine tests are recommended: [19] Complete blood count
A 2-day CPET is a cardiopulmonary exercise test given on two successive days to measure the effect of post-exertional malaise (PEM) on a patient's ability to exercise. [1] [2] PEM is a cardinal symptom of myalgic encephalomyelitis/chronic fatigue syndrome and is common in long COVID as well. [3]
The term chronic fatigue syndrome is criticised for focusing on a single symptom, while its use has lead many to confuse ME/CFS with general chronic fatigue. The term “fatigue” trivialises the illness and discourages research into potential treatments. [91]
The ME association was skeptical of the former guidance recommended by The National Institute for Health and Care Excellence (NICE) for primary treatment of ME/CFS. The MEA considers CBT with GET not safe for ME/CFS patients, or not effective. The ME Association recommends that persons with ME/CFS consider a pacing approach to the illness.
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