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The term "biguanidine" often refers specifically to a class of drugs that function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. [4] Examples include: Metformin - widely used in treatment of diabetes mellitus type 2; Phenformin - withdrawn from the market in most countries due to toxic effects
It was demonstrated that the increase is due to de novo synthesis of fresh enzyme. In 1991, during the investigation of the expression of early-response genes in fibroblasts transformed with Rous sarcoma virus, a novel mRNA transcript that was similar, but not identical, to the seminal COX enzyme was identified.
This page was last edited on 14 May 2014, at 13:04 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply ...
Researchers report the world's first artificial synthesis of starch. The material essential for many products and the most common carbohydrate in human diets was made from CO 2 in a cell-free process and could reduce land, pesticide and water use as well as greenhouse gas emissions while increasing food security.
[14] Plunkett described the discovery and development at the 1986 American Chemical Society symposium on the History of High Performance Polymers. [ 17 ] : 261–266 He said that he and his assistant, Jack Rebok, had opened a tetrafluoroethylene (TFE) cylinder to examine an unusual white powder that had prevented the TFE gas from flowing out.
However, if you locked in a rate above 7% recently, keep an eye on rates in the coming months — but remember that refinancing comes with closing costs that typically run 3% to 6% of your loan ...
Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.
*comparator to ethyl group (IC 50 = 16,7) In table 2, the in vitro activity changes depending on the compound in the C-4 region of the proximal phenyl ring (X). Small methyl groups or other halogen atoms in the C-4 position gave IC 50 ranging from 0.72–36.7 (given that the phenyl with 2-furyl is in the ring position). [3]