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  2. Noroxymorphone - Wikipedia

    en.wikipedia.org/wiki/Noroxymorphone

    key:hlmsizpqbsyunl-ipoqpsjvsa-n Noroxymorphone is an opioid [ 1 ] which is both a metabolite of oxymorphone and oxycodone and is manufactured specifically as an intermediate in the production of narcotic antagonists such as naltrexone and others.

  3. Tapentadol - Wikipedia

    en.wikipedia.org/wiki/Tapentadol

    It is 18 times less potent than morphine in terms of binding to human μ-opioid receptors in in vitro research on human tissue. [49] In vivo , only 32% of an oral dose of tapentadol will survive first pass metabolism and proceed to the bloodstream to produce its effects on the central and peripheral nervous systems of the patient.

  4. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  5. Morphine - Wikipedia

    en.wikipedia.org/wiki/Morphine

    After IM or SC injections, morphine plasma levels peak in approximately 20 min, and, after oral administration, levels peak in approximately 30 min. [81] Morphine is metabolised primarily in the liver and approximately 87% of a dose of morphine is excreted in the urine within 72 h of administration.

  6. List of opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_opioids

    Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."

  7. Philippine House Committee on Dangerous Drugs - Wikipedia

    en.wikipedia.org/wiki/Philippine_House_Committee...

    Party-list: Manuel Cabochan MAGDALO: Party-list: Leonardo Babasa Jr. PDP–Laban: Zamboanga del Sur: 2nd: Macnell M. Lusotan MARINO Party-list: Julienne Baronda NUP: Iloilo City: Lone: Members for the Minority Arnolfo Teves Jr. PDP–Laban: Negros Oriental: 3rd: Sergio Dagooc APEC: Party-list: Francisca Castro ACT TEACHERS: Party-list: Argel ...

  8. Normorphine - Wikipedia

    en.wikipedia.org/wiki/Normorphine

    The compound has relatively little opioid activity in its own right, [3] [4] but is a useful intermediate which can be used to produce both opioid antagonists such as nalorphine, and also potent opioid agonists such as N-phenethylnormorphine. [5] with its formation from morphine catalyzed by the liver enzymes CYP3A4 and CYP2C8. [6]

  9. Single Convention on Narcotic Drugs - Wikipedia

    en.wikipedia.org/wiki/Single_Convention_on...

    The Single Convention on Narcotic Drugs, 1961 (Single Convention, 1961 Convention, or C61) is an international treaty that controls activities (cultivation, production, supply, trade, transport) involving specific narcotic drugs and lays down a system of regulations (licenses, measures for treatment, research, etc.) for their medical and scientific uses, concluded under the auspices of the ...