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In polymer chemistry, in situ polymerization is a preparation method that occurs "in the polymerization mixture" and is used to develop polymer nanocomposites from nanoparticles. There are numerous unstable oligomers ( molecules ) which must be synthesized in situ (i.e. in the reaction mixture but cannot be isolated on their own) for use in ...
Nanomedicine is the medical application of nanotechnology. [1] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines.
The process of free radical polymerization of a single type of monomer, in this case, N-isopropylacrylamide, to form the polymer is known as a homopolymerization. The radical initiator azobisisobutyronitrile (AIBN) is commonly used in radical polymerizations.
Polymer nanoscience is the study and application of nanoscience to polymer-nanoparticle matrices, where nanoparticles are those with at least one dimension of less than 100 nm. The transition from micro- to nano-particles lead to change in its physical as well as chemical properties.
Nanoparticle drug delivery focuses on maximizing drug efficacy and minimizing cytotoxicity. Fine-tuning nanoparticle properties for effective drug delivery involves addressing the following factors. The surface-area-to-volume ratio of nanoparticles can be altered to allow for more ligand binding to the surface. [4]
Nanoparticles can generally carry drugs in two ways: drugs can either be bound to the outside of the nanoparticles or packed within the polymeric matrix of the nanoparticles. [14] Smaller nanoparticles have higher surface area ratios and can thus bind a high quantity of drug, while larger nanoparticles can encapsulate more of the drug within ...
Research on nanoparticles and their chitosan nanoparticles grew in popularity in the early 1990s. [1] [2] [3] mainly due to its biodegradability and biocompatibility nature. Chitosan, due to its molecular structure, can be dissolved well within a variety of solvents and a variety of biologics, such as acids like formic and lactic acid. [3]
Nonmetallic nanoparticles and nanomaterials: Size-dependent behavior of mechanical properties is still not clear in the case of polymer nanomaterials however, in one research by Lahouij they found that the compressive moduli of polystyrene nanoparticles were found to be less than that of the bulk counterparts.
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