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A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is widely used in clinical trials for newer medicines to investigate therapeutic effectiveness and safety.
Peak-to-trough ratio in pharmacokinetics is the ratio of peak (C max) and trough (C min) levels of a drug over its dosing interval (τ) at steady state.. Peak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing ...
The variation can be described as a periodic function, which in turn can be split into a DC component (the peak value) [a] and an AC component (peak minus trough). [42] The ratio of the AC component to the DC component, expressed as a percentage, is known as the (peripheral) perfusion index (Pi) for a pulse, and typically has a range of 0.02% ...
A trough is an elongated area of lower air pressure. Since pressure is closely linked to wind, there are often changes in wind direction across a trough. If a trough forms in the mid-latitudes, a temperature difference at some distance between the two sides of the trough usually exists and the trough might become a weather front at some
Also actiniform. Describing a collection of low-lying, radially structured clouds with distinct shapes (resembling leaves or wheels in satellite imagery), and typically organized in extensive mesoscale fields over marine environments. They are closely related to and sometimes considered a variant of stratocumulus clouds. actinometer A scientific instrument used to measure the heating power of ...
High levels of dietary fructose induce a similar process. The fructose is converted into a precursor of fat in the liver, called lipids. Those lipids can then feed the tumor.”
“The thing that has impressed me with this team is that they don’t get down,” Chiefs head coach Andy Reid said Monday. “That’s not what they are.
Wondering how much protein you need to build muscle? Learn the science behind muscle growth, daily protein goals, and expert-backed tips for optimal results.