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Cabergoline confers a significant reduction in the risk of OHSS in high risk women according to a Cochrane review of randomized studies, but the included trials did not report the live birth rates or multiple pregnancy rates. [6] Cabergoline, as well as other dopamine agonists, might reduce the severity of OHSS by interfering with the VEGF ...
Severe cases often require hospitalization, removal of fluid from the abdomen, and replacement of fluid in the blood. OHSS is most prevalent in very high responders, almost always those with more than 20 developing ovarian follicles, who are triggered with hCG. One means of greatly reducing OHSS risk is to trigger with GnRH agonist instead of hCG.
OHSS may be caused by “an excess of substances made by the hyperstimulated ovaries that increases leakage of fluid rich in protein out of the blood vessels, where it needs to be, to other spaces ...
A Cochrane review estimated that using GnRH agonist instead of hCG in IVF decreases the risk of mild, moderate or severe OHSS with an odds ratio of approximately 0.15. The review estimated that, for a woman with a 5% risk of mild, moderate or severe OHSS with the use of HCG, the risk of OHSS with the use of a GnRH agonist would be between 0 and ...
Theca lutein cyst is a type of bilateral functional ovarian cyst filled with clear, straw-colored fluid. These cysts result from exaggerated physiological stimulation (hyperreactio luteinalis) due to elevated levels of beta-human chorionic gonadotropin (beta-hCG) or hypersensitivity to beta-hCG.
Ferritin levels are undoubtedly important for diagnosing iron deficiency. However, healthcare providers need to assess the ferritin levels in conjunction with a patient’s whole picture of health ...
The addition of estrogen or hCG as adjunctives to progesterone do not appear to affect outcomes pregnancy rate and live birth rate in IVF. [1] In fact, luteal support with human chorionic gonadotropin (hCG) alone or as a supplement to progesterone has been associated with a higher risk of ovarian hyperstimulation syndrome (OHSS). [2]
Specifically, it may increase the risk of birth defects, reduced growth, and early pregnancy loss. For some people, the benefits of taking Ozempic while pregnant may outweigh the risks.
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