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A pleural effusion is accumulation of excessive fluid in the pleural space, the potential space that surrounds each lung.Under normal conditions, pleural fluid is secreted by the parietal pleural capillaries at a rate of 0.6 millilitre per kilogram weight per hour, and is cleared by lymphatic absorption leaving behind only 5–15 millilitres of fluid, which helps to maintain a functional ...
Sildenafil is used as a preventive treatment for altitude-induced pulmonary edema and pulmonary hypertension. [ 38 ] [ 39 ] Sildenafil's mechanism of action is via phosphodiesterase inhibition which raises cGMP, resulting in pulmonary arterial vasodilation and inhibition of smooth muscle cell proliferation and indirectly fluid formation in the ...
Hydrothorax is the synonym of pleural effusion in which fluid accumulates in the pleural cavity. This condition is most likely to develop secondary to congestive heart failure, following an increase in hydrostatic pressure within the lungs. More rarely, hydrothorax can develop in 10% of patients with ascites which is called hepatic hydrothorax ...
Intrapleural fibrinolysis with urokinase decreased the need for surgery but there is a trend to increased serious side effects. [18] Approximately 15 to 40 percent of people require surgical drainage of the infected pleural space because of inadequate drainage due to clogging of the chest tube or loculated empyema. [19]
Pleural effusion involving fibrinous exudates in the fluid may be called fibrinous pleurisy, which sometimes occurs as a later stage of pleurisy. A person can develop a pleural effusion in the absence of pleurisy. For example, pneumonia, heart failure, cancer, or a pulmonary embolism can lead to a pleural effusion.
Edema may be described as pitting edema, or non-pitting edema. [32] Pitting edema is when, after pressure is applied to a small area, the indentation persists after the release of the pressure. Peripheral pitting edema, as shown in the illustration, is the more common type, resulting from water retention.
CT scans can more readily differentiate whether pleural thickening is due to extra fat deposition or true pleural thickening than X-rays. [3] If a fibrothorax is severe, the thickening may restrict the lung on the affected side causing a loss of lung volume. [7] Additionally, the mediastinum may be physically shifted toward the affected side. [3]
A parapneumonic effusion is a type of pleural effusion (accumulation of fluid in the pleural cavity) that arises as a result of a pneumonia, lung abscess, or bronchiectasis. [1] There are three types of parapneumonic effusions: uncomplicated effusions, complicated effusions, and empyema. Uncomplicated effusions generally respond well to ...