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2. Citrulline - Wikipedia

   en.wikipedia.org/wiki/Citrulline

   Citrulline is also produced as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine, catalyzed by nitric oxide synthase. In the yeast species Saccharomyces cerevisiae, citrulline is a metabolic intermediate in the latter, cytosolic half of the arginine biosynthesis pathway.

3. Malic acid - Wikipedia

   en.wikipedia.org/wiki/Malic_acid

   Malate plays an important role in biochemistry. In the C4 carbon fixation process, malate is a source of CO 2 in the Calvin cycle. In the citric acid cycle, (S)-malate is an intermediate, formed by the addition of an -OH group on the si face of fumarate. It can also be formed from pyruvate via anaplerotic reactions.

4. Citrate–malate shuttle - Wikipedia

   en.wikipedia.org/wiki/Citrate–malate_shuttle

   Citrate ion Malate ion. The citrate-malate shuttle is a series of chemical reactions, commonly referred to as a biochemical cycle or system, that transports acetyl-CoA in the mitochondrial matrix across the inner and outer mitochondrial membranes for fatty acid synthesis. [1] Mitochondria are enclosed in a double membrane.

5. How Long Does It Take for L-Citrulline to Work for ED? - AOL

   www.aol.com/long-does-l-citrulline-ed-105700234.html

   One source recommends an L-citrulline dosage of 2,000 milligrams three times a day, or 1.76 grams of citrulline malate for every 1 gram of citrulline you might take for circulatory health.

6. Urea cycle - Wikipedia

   en.wikipedia.org/wiki/Urea_cycle

   This malate is then oxidized to oxaloacetate by cytosolic malate dehydrogenase, generating a reduced NADH in the cytosol. Oxaloacetate is one of the keto acids preferred by transaminases , and so will be recycled to aspartate , maintaining the flow of nitrogen into the urea cycle.

7. Citrullination - Wikipedia

   en.wikipedia.org/wiki/Citrullination

   Citrulline is not one of the 20 standard amino acids encoded by DNA in the genetic code. Instead, it is the result of a post-translational modification. Citrullination is distinct from the formation of the free amino acid citrulline as part of the urea cycle or as a byproduct of enzymes of the nitric oxide synthase family.