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Common side effects include heartburn, nausea, indigestion, and abdominal pain. [8] As with other NSAIDs, potential side effects include gastrointestinal bleeding. [10] Long-term use has been associated with kidney failure, and rarely liver failure, and it can exacerbate the condition of patients with heart failure. [8]
Doctors were surprised by the results after looking at the health risks of common anti-inflammatory drugs.
Ulceration risk increases with therapy duration, and with higher doses. To minimize GI side effects, it is prudent to use the lowest effective dose for the shortest period of time—a practice that studies show is often not followed. Over 50% of patients who take NSAIDs have sustained some mucosal damage to their small intestine. [77]
As osteoarthritis is a disease commonly found in the elderly (>65 years old), oral NSAIDs are seldom used as their systemic side effects are more severe in elderly patients. [8] Therefore, topical NSAIDs are used for osteoarthritis to exert its local analgesic effects and minimize their systemic side effects in elderly patients. [8]
When patients are asked about their ... drugs (NSAIDs), like ibuprofen (Advil® or Motrin®) or naproxen (Aleve®). ... teach you exercises to help with the effects of arthritis. Physical therapy ...
A new study has suggested that damage to the upper gastrointestinal tract from conditions such as reflux, peptic ulcers, and prolonged use of NSAIDS may increase Parkinson’s risk by 76%.
The role for these products is between just the use of simple analgesics (paracetamol or ibuprofen) and the triptan class of drugs; although the latter are not options during pregnancy. [7] In the elderly although triptans are generally avoided, so too are antiemetics such as metoclopramide due to higher risks of side effects.
Health care providers and patients may have difficulty communicating with each other about how pain responds to treatments. [6] There is a risk in many types of pain management for the patient to take treatment that is less effective than needed or which causes other difficulties and side effects. [6]
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