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In aphasia (sometimes called dysphasia), [a] a person may be unable to comprehend or unable to formulate language because of damage to specific brain regions. [2] The major causes are stroke and head trauma; prevalence is hard to determine, but aphasia due to stroke is estimated to be 0.1–0.4% in the Global North. [3]
Global aphasia typically results from an occlusion to the trunk of the middle cerebral artery (MCA), [2] which affects a large portion of the perisylvian region of the left cortex. [7] Global aphasia is usually a result of a thrombotic stroke, which occurs when a blood clot forms in the brain's blood vessels.
Survivors with global aphasia may have great difficulty understanding and forming words and sentences, and generally experience a great deal of difficulty when trying to communicate. [2] With considerable speech therapy rehabilitation, global aphasia may progress into expressive aphasia or receptive aphasia. [citation needed]
Transcortical sensory aphasia is characterized as a fluent aphasia. Fluency is determined by direct qualitative observation of the patient’s speech to determine the length of spoken phrases, and is usually characterized by a normal or rapid rate; normal phrase length, rhythm, melody, and articulatory agility; and normal or paragrammatic speech. [5]
The Boston Diagnostic Aphasia Examination is a neuropsychological battery used to evaluate adults suspected of having aphasia, and is currently in its third edition. [1] It was created by Harold Goodglass and Edith Kaplan. The exam evaluates language skills based on perceptual modalities (auditory, visual, and gestural), processing functions ...
Mixed transcortical aphasia is characterized by severe speaking and comprehension impairment, but with preserved repetition. [6] People who suffer mixed transcortical aphasia struggle greatly to produce propositional language or to understand what is being said to them, yet they can repeat long, complex utterances or finish a song once they hear the first part.
Anomic aphasia (word retrieval failures) Phonemic paraphasia (sound errors in speech e.g. 'gat' for 'cat') Agrammatism (using the wrong tense or word order) As the disease develops, speech quantity decreases and many patients become mute. Cognitive domains other than language are rarely affected early on.
Logopenic progressive aphasia (LPA) is a variant of primary progressive aphasia. [1] It is defined clinically by impairments in naming and sentence repetition. [ 2 ] It is similar to conduction aphasia and is associated with atrophy to the left posterior temporal cortex and inferior parietal lobule .
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