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Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin -regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac).
TUG releases the GLUT4 containing vesicles (GSVs) in response to insulin stimulation which allows it to move to the plasma membrane. [2] TUG has an N-terminal ubiquitin-like protein domain (UBL1) which in similar proteins appears to participate in protein-protein interactions. [2]
GLUT4: Expressed in adipose tissues and striated muscle (skeletal muscle and cardiac muscle). Is the insulin-regulated glucose transporter. Responsible for insulin-regulated glucose storage. GLUT14: Expressed in testes: similarity to GLUT3 [12]
De novo identification tool for small molecules that works with Microsoft Excel (2010, 2013, 2016 and 2019). This software treats small molecules as mathematical partitions of the molecular mass and generates subfragment formulas with atoms that are sets of partitions comprising the molecular formula. Rational Numbers SPS Proprietary
PRIDE Converter is a tool, written in the Java programming language, that converts 15 different input mass spectrometry data formats into PRIDE XML via a wizard-like graphical user interface. It is freely available and is open source under the permissive Apache License .
n/a Ensembl ENSG00000125520 n/a UniProt Q9NR83 n/a RefSeq (mRNA) NM_020062 n/a RefSeq (protein) NP_064446 n/a Location (UCSC) Chr 20: 63.74 – 63.74 Mb n/a PubMed search n/a Wikidata View/Edit Human SLC2A4 regulator is a protein that in humans is encoded by the SLC2A4RG gene. The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier ...
Insulin secretion results in positive feedback in different ways. Firstly, insulin increases the uptake of glucose from blood by the translocation and exocytosis of GLUT4 storage vesicles in the muscle and fat cells. Secondly, it promotes the conversion of glucose into triglyceride in the liver, fat, and muscle cells.
A tool to annotate phage genomes. Phages [43] SplicePredictor Method to identify potential splice sites in (plant) pre-mRNA by sequence inspection using Bayesian statistical models: Eukaryotes [44] VEIL Hidden Markov model to find genes in vertebrate DNA Server: Eukaryotes [45]