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The prognosis is poor and supportive treatment is necessary. Recovery in cats may take up to one year. [10] Giant axonal neuropathy is a rare disease in the German Shepherd dog. It usually becomes evident between the ages of 14 and 16 months. [1] Symptoms include rear limb weakness, decreased reflexes, muscle atrophy, megaesophagus, and loss of ...
Diabetes in cats can be classified into the following: Type 1 diabetes, in which the immune system attacks the pancreas, is "extremely rare" in cats, unlike in dogs and humans. [2] Type 2 diabetes is responsible for 80–95% of diabetic cases. They are generally severely insulin dependent by the time symptoms are diagnosed.
Tight control of blood glucose can reverse the changes of diabetic neuropathy if the neuropathy and diabetes are recent in onset. This is the primary treatment of diabetic neuropathy that may change the course of the condition as the other treatments focus on reducing pain and other symptoms.
Metformin can also impair the absorption of calcium and vitamin B12 from your gut, Dr. Gupta adds, “so it is important to take additional vitamin B12 supplementation and maintain adequate ...
Taking metformin with food can reduce the risk of gastrointestinal side effects, so try taking it with the same meal each day. If you take one metformin tablet a day, it’s usually recommended ...
“The improvement in these symptoms with metformin seems likely due to its metabolic effects at the cellular level,” Dr. Cutler says. “But it is not a cure and does not work for everyone.”
Additionally, BP control in those with diabetes is helpful, while intravenous immunoglobulin is used for multifocal motor neuropathy. [ 1 ] According to Lopate, et al., methylprednisolone is a viable treatment for chronic inflammatory demyelinative polyneuropathy (which can also be treated with intravenous immunoglobulin).
Affected cats may also display poor judgement of distance, and some cats may develop a rapid, crouching, hypermetric gait. Some affected cats may exhibit an abnormal head tilt, tremors, a vacant stare, excessive salivation, decreased grooming behaviors, polyphagia , and dilated pupils. [ 3 ]