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  2. Beta blocker - Wikipedia

    en.wikipedia.org/wiki/Beta_blocker

    Beta blockers, due to their antagonism at beta-1 adrenergic receptors, inhibit both the synthesis of new melatonin and its secretion by the pineal gland. The neuropsychiatric side effects of some beta blockers (e.g. sleep disruption, insomnia) may be due to this effect. [99]

  3. What is a beta blocker? Why they are vital to those with ...

    www.aol.com/beta-blocker-why-vital-those...

    The Cleveland Clinic classified beta blockers into two categories, cardioselective and nonselective, according to its website. The latter is for medicines that block the B1 receptors found in the ...

  4. Adrenergic blocking agent - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_blocking_agent

    Overdose of lipophilic beta-1 blocker can disturb neurologic functioning, which eventually lead to altered mental states. [5] To mitigate the toxicity of Beta-1 blocker, glucagon, salts like calcium and sodium bicarbonate, magnesium sulfate are used to reverse beta-1-blocker effect and treating hypotension respectively. [5]

  5. Adrenergic neuron blockers - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_neuron_blockers

    Beta 1 blockers bind to the beta 1 receptor without activating it, inhibiting the receptor-mediated effects. [4] The beta-1 receptor is a G-protein-coupled receptor with the Gs alpha subunit as its main signaling protein. [ 4 ]

  6. Discovery and development of beta-blockers - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Figure 1: The chemical structure of dichloroisoprenaline or dichloroisoproterenol (), abbreviated DCI — the first β-blocker to be developed. β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also used for hypertension, congestive heart failure and certain arrhythmias. [1]

  7. Bisoprolol - Wikipedia

    en.wikipedia.org/wiki/Bisoprolol

    Bisoprolol, sold under the brand name Zebeta among others, is a beta blocker which is selective for the beta-1 receptor [7] and used for cardiovascular diseases, [7] including tachyarrhythmias, high blood pressure, angina, and heart failure. [7] [8] It is taken by mouth. [7]

  8. Beta-1 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-1_adrenergic_receptor

    The beta-1 adrenergic receptor (β 1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors. [5] It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein that is expressed predominantly in cardiac tissue. In addition to cardiac tissue, beta ...

  9. Propranolol - Wikipedia

    en.wikipedia.org/wiki/Propranolol

    Propranolol is a non-selective β-adrenergic receptor antagonist, or beta blocker; [61] that is, it blocks the action of epinephrine (adrenaline) and norepinephrine (noradrenaline) at both β 1-and β 2-adrenergic receptors.

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