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  2. Beta-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Beta-2_adrenergic_receptor

    The beta-2 adrenergic receptor2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric G s proteins, increases cAMP, and, via downstream L-type calcium channel interaction, mediates physiologic responses such as smooth ...

  3. Adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_receptor

    The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-22) antagonists and alpha-22) agonists, which are used to treat high ...

  4. Beta2-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta2-adrenergic_agonist

    Beta 2-adrenergic agonists, also known as adrenergic β 2 receptor agonists, are a class of drugs that act on the β 2 adrenergic receptor. Like other β adrenergic agonists , they cause smooth muscle relaxation. β 2 adrenergic agonists' effects on smooth muscle cause dilation of bronchial passages , vasodilation in muscle and liver ...

  5. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    β1 receptors make up to 75% of all beta receptors and are predominantly located in the heart. β2 receptors are found in vascular and bronchial smooth muscle. β3 receptors, which are presumed to be involved in fatty acid metabolism, are located in the adipocytes. [15] Figure 2: GPCR cycle

  6. Beta-adrenergic agonist - Wikipedia

    en.wikipedia.org/wiki/Beta-adrenergic_agonist

    Activation of β 2 receptors induces smooth muscle relaxation in the lungs, gastrointestinal tract, uterus, and various blood vessels. Increased heart rate and heart muscle contraction are associated with the β1 receptors; however, β 2 cause vasodilation in the myocardium. [citation needed] β3 receptors are mainly located in adipose tissue. [5]

  7. Adrenergic blocking agent - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_blocking_agent

    Beta 3 receptor is a G-protein coupled receptor, similar to beta-1 and beta-2 receptors. [7] The receptor is involved in G-as activation. [7] The receptor will also stimulate adenylyl cyclase. [7] Eventually, it will lead to effects like increase of tryptophan and 5-hydroxytryptamine level, increase of lipolysis in adipose tissue. [7]

  8. NYT ‘Connections’ Hints and Answers Today, Thursday, February 13

    www.aol.com/nyt-connections-hints-answers-today...

    2. Different ways to show feelings of gratitude. 3. Auxillary words that indicate "possibility" or "necessity." 4. The words in this category precede a four-letter noun (hint: the noun typically ...

  9. Alpha-4 beta-2 nicotinic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-4_beta-2_nicotinic...

    The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, [1] consisting of α4 and β2 subunits. [2] It is located in the brain , where activation yields post- and presynaptic excitation , [ 2 ] mainly by increased Na + and K + permeability.