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They show that either the development of the cerebellum is tightly linked to that of the rest of the brain or that neural activities taking place in the cerebellum were important during Hominidae evolution. Due to the cerebellum's role in cognitive functions, the increase in its size may have played a role in cognitive expansion. [86]
The cerebellar granule cells also play a role in orchestrating the tonic conductances which control sleep in conjunction with the ambient levels of GABA which are found in the brain. Dentate granule cells. Loss of dentate gyrus neurons from the hippocampus results in spatial memory deficits.
Cerebellar TMS is a relatively new field that is undergoing experimental research. A review of scientific literature (2024) has identified hypotheses of underlying processes of different non-invasive neurostimulation techniques. [3] Data analysis revealed that mitochondrial activity plays a central role in all of them.
Regardless of the mechanism, studies of cerebellar-dependent motor tasks show that cerebral cortical plasticity is crucial for motor learning, even if not necessarily for storage. [13] The basal ganglia also play an important role in memory and learning, in particular in reference to stimulus-response associations and the formation of habits ...
Such brain parts as the cerebellum, striatum, cerebral cortex, hippocampus, and amygdala are thought to play an important role in memory. For example, the hippocampus is believed to be involved in spatial and declarative memory, as well as consolidating short-term into long-term memory.
The cerebellum, and especially the cerebellar cortex, is critical for coordinating motor outputs during skilled tasks, as well as the process of stabilizing newly formed motor skills. [17] Damage to the cerebellum can occur through a number of causes including trauma, alcoholism, chronic degenerative diseases such as olivopontocerebellar ...
This period is an important developmental stage of the cerebellum. The expansion of the EGL precursor cells creates a large population of neurons that outnumber Purkinje cells 250:1 in the adult cerebellar cortex. [6] The granule neurons in EGL express genes that play a specific and crucial role in cell proliferation.
The cerebellum's anterior and posterior lobes appear to play a role in the coordination and smoothing of complex motor movements, and the flocculonodular lobe in the maintenance of balance [36] although debate exists as to its cognitive, behavioural and motor functions.