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2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate. The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips. [2]
An incision wound closed with Dermabond, a cyanoacrylate-based medical adhesive. Cyanoacrylate glue is widely used in human and veterinary medicine. [6] It was in veterinary use for mending bone, hide, and tortoise shell by the early 1970s or before.
There are three cyanoacrylate compounds currently available as topical skin adhesives. 2-Octyl cyanoacrylate is marketed as Dermabond, SurgiSeal, and more recently LiquiBand Exceed. n-Butyl cyanoacrylate is marketed as Histoacryl, Indermil, GluStitch, GluSeal, PeriAcryl, and LiquiBand. The compound ethyl 2-cyanoacrylate is available as Epiglu. [3]
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A dermal adhesive (or skin glue) is a glue used to close wounds in the skin as an alternative to sutures, staples, or clips.. Glued closure results in less scarring and is less prone to infection than sutured or stapled closure.
The arm of a 5 year old with an incision wound from broken glass. The wound was sealed with Dermabond approximately 14 hours previously. Date: 30 July 2015 (according to Exif data) Source: Own work: Author: ragesoss
These worked well but had the disadvantage of having to be stored in the refrigerator, were exothermic so they stung the patient, and the bond was brittle. Nowadays, the longer chain polymer, 2-octyl cyanoacrylate, is the preferred medical grade glue. It is available under various trade names, such as LiquiBand, SurgiSeal, FloraSeal, and Dermabond.
DePuy Synthes (/ d ə ˈ p j uː /) is a franchise of orthopaedic and neurosurgery companies.Acquired by Johnson & Johnson in 1998, its companies form part of the Johnson & Johnson MedTech business segment.
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