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Pleural contamination with asbestos or other mineral fibers has been shown to cause cancer. Long thin asbestos fibers (blue asbestos, amphibole fibers) are more potent carcinogens than "feathery fibers" (chrysotile or white asbestos fibers). [28] However, there is now evidence that smaller particles may be more dangerous than the larger fibers.
Globally, head and neck cancer accounts for 650,000 new cases of cancer and 330,000 deaths annually on average. In 2018, it was the seventh most common cancer worldwide, with 890,000 new cases documented and 450,000 people dying from the disease. [12] The risk of developing head and neck cancer increases with age, especially after 50 years.
Some substances cause cancer primarily through their physical, rather than chemical, effects on cells. [32] A prominent example of this is prolonged exposure to asbestos, naturally occurring mineral fibers which are a major cause of mesothelioma, which is a cancer of the serous membrane, usually the serous membrane surrounding the lungs. [32]
Peritoneal mesothelioma is the name given to the cancer that attacks the lining of the abdomen. This type of cancer affects the lining that protects the contents of the abdomen and which also provides a lubricating fluid to enable the organs to move and work properly.
Mesothelioma: (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Cancer cells can also metastasize (spread) from their original site to other parts of the body. Most cases of mesothelioma begin in the pleura or ...
Asbestosis is long-term inflammation and scarring of the lungs due to asbestos fibers. [4] Symptoms may include shortness of breath, cough, wheezing, and chest tightness. [1] Complications may include lung cancer, mesothelioma, and pulmonary heart disease. [1] [9] Asbestosis is caused by breathing in asbestos fibers.
An estimated 0.5% of polytrauma patients treated in trauma centers have TBI. [10] The incidence is estimated at 2% in blunt chest and neck trauma and 1–2% in penetrating chest trauma. [10] Laryngotracheal injuries occur in 8% of patients with penetrating injury to the neck, and TBI occurs in 2.8% of blunt chest trauma deaths. [6]
A combination of docetaxel and gemcitabine could be an effective chemotherapy regimen in patients with advanced soft-tissue sarcoma. [15] [16] Outcomes are better for patients who are seen (and ideally treated) at expert sarcoma centers. [17] In the United States, these are generally found in NCI-designated cancer centers.
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