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Sarcopenia (ICD-10-CM code M62.84 [1]) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors.
Muscle-atrophy can be induced in pre-clinical models (e.g. mice) to study the effects of therapeutic interventions against muscle-atrophy. Restriction of the diet, i.e. caloric restriction, leads to a significant loss of muscle mass within two weeks, and loss of muscle-mass can be rescued by a nutritional intervention. [35]
The results of this study suggested that following a diet high in fast food, processed red meat, and soda but low in fruits and vegetables may speed up aging, even in young adults.
You can’t go far lately without seeing news and social media coverage of GLP-1 (glucagon-like peptide-1) receptor agonists like Ozempic®, Wegovy®, Mounjaro®, and Zepbound®.
The concept of "protein-sparing modified fast" (PSMF) was described by George Blackburn in the early 1970s as an intensive weight-loss diet designed to mitigate the harms associated with protein-calorie malnutrition [8] and nitrogen losses induced by either acute illness or hypocaloric diets in patients with obesity, in order to adapt the patient's metabolism sufficiently to use endogenous fat ...
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Age-related changes are observed in fine structure of spindle nerve innervation in the form of axonal swelling and expanded/abnormal endplates. [6] When subject to a task of proprioception, the elderly show increased cocontraction of agonist-antagonist muscles, perhaps to increase gamma drive and spindle sensitivity. It is believed to be used ...
In males, mean percentage body fat ranged from 23% at age 16–19 years to 31% at age 60–79 years. In females, mean percentage body fat ranged from 32% at age 8–11 years to 42% at age 60–79 years. But it is important to recognise that women need at least 9% more body fat than men to live a normal healthy life. [2]