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Melanoma is a group of serious skin cancers that arise from pigment cells (melanocytes); acral lentiginous melanoma is a kind of lentiginous [8] skin melanoma. [6] ALM makes up less than 5% of all melanomas, but is considered the most common subtype in people with darker skin and is rare in people with lighter skin types. [9]
59,800 (2015) [6] Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [1][2] In women, melanomas most commonly occur on the legs; while in men, on the back. [2]
Post excision pathology was "Lentigo maligna - Melanoma in situ". Lentigo maligna is where melanocyte cells have become malignant and grow continuously along the stratum basale of the skin, [1] but have not invaded below the epidermis. [2] Lentigo maligna is not the same as lentigo maligna melanoma, as detailed below.
He had acral lentiginous melanoma that appeared as a dark spot under his toenail. ALM typically develops under nails, on the soles of the feet or the palms of the hands and is the most common form ...
The mortality rate of basal-cell and squamous-cell carcinoma is around 0.3%, causing 2000 deaths per year in the US. In comparison, the mortality rate of melanoma is 15–20% and it causes 6500 deaths per year. [67]: 29, 31 Even though it is much less common, malignant melanoma is responsible for 75% of all skin cancer-related deaths. [68]
This type of cancer — called acral lentiginous melanoma — tends to be more aggressive than other melanomas. Singer Bob Marley died at the age of 36 after being diagnosed with the disease.
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Lentigo maligna melanoma. Lentigo maligna melanoma is a melanoma that has evolved from a lentigo maligna, [1]: 695 as seen as a lentigo maligna with melanoma cells invading below the boundaries of the epidermis. [2] They are usually found on chronically sun damaged skin such as the face and the forearms of the elderly.
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