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Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [90] Prostate cancer is rare in those under 40 years old, [91] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [92]
Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA damage and genomic instability. [1][2] A minority of cancers are due to inherited genetic mutations. [3] Most cancers are related to environmental, lifestyle, or behavioral exposures. [4]
The study projects that overall cancer cases among men will increase from 10.3 million in 2022 to 19 million in 2050, an increase of 84%. Cancer deaths were projected to rise from 5.4 million in ...
The leading cause of death in both males and females is lung cancer, which contributes to 26.8% of all cancer deaths. Statistics indicate that between the ages of 20 and 50 years, the incidence rate of cancer is higher amongst women whereas after 50 years of age, the incidence rate increases in men.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [ 2 ][ 7 ] These contrast with benign tumors, which do not spread. [ 7 ] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. [ 1 ]
The incidence of colon cancer has been rising for at least the last two decades, when it was the fourth-leading cause of cancer death for both men and women under 50.
Primary liver cancer is globally the sixth-most frequent cancer and the fourth-leading cause of death from cancer. [7] [10] In 2018, it occurred in 841,000 people and resulted in 782,000 deaths globally. [7] Higher rates of liver cancer occur where hepatitis B and C are common, including Asia and sub-Saharan Africa. [3]
As of 2012, it is the second most common cause of cancer in women (9.2% of diagnoses) and the third most common in men (10.0%) [14]: 16 with it being the fourth most common cause of cancer death after lung, stomach, and liver cancer. [200] It is more common in developed than developing countries. [201]
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