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Checkpoint inhibitor induced colitis is an inflammatory condition affecting the colon , which is caused by cancer immunotherapy (checkpoint inhibitor therapy). Symptoms typically consist of diarrhea, abdominal pain and rectal bleeding. Less commonly, nausea and vomiting may occur, which may suggest the present of gastroenteritis. The severity ...
A human colon is considered abnormally enlarged if it has a diameter greater than 12 cm [3] in the cecum (it is usually less than 9 cm [4]), greater than 6.5 cm [3] in the rectosigmoid region and greater than 8 cm [3] for the ascending colon. The transverse colon is usually less than 6 cm in diameter. [4] A megacolon can be either acute or ...
There is a strong link between FGIDs and psychosocial factors. Psychosocial factors influence the functioning of the GI tract through the brain-gut axis, including the GI tract's motility, sensitivity, and barrier function. Psychosocial factors also affect experience and behavior, treatment selection, and clinical outcome.
Credit - Illustration by TIME; agung fatria/iStockphoto/Getty Images. S omewhere between 60 and 70 million Americans have digestive conditions like inflammatory bowel disease, acid reflux, chronic ...
Colon-cancer treatment Treatment varies depending on how far the cancer has advanced and where in the bowel it is, but it can include surgery, radiation therapy, chemotherapy, and immunotherapy.
There is an ongoing discussion, however, that the term "chronic enteropathy" might be better to use than "inflammatory bowel disease" in dogs because it differs from IBD in humans in how the dogs respond to treatment. For example, many dogs respond to only dietary changes compared to humans with IBD, who often need immunosuppressive treatment ...
The total removal of the colon, called a colectomy or resection of affected parts of the colon may be needed if part of the gut dies (for instance toxic megacolon), or if there is a localized area of dysmotility. Gastric and colonic pacemakers have been tried. These are strips placed along the colon or stomach which create an electric discharge ...
Although the use of antibodies to treat diseases can be dated back to the 1800s, biologic therapy as we know it today is a relatively new concept for the treatment of inflammatory bowel disease. [9] The previous treatment options had many shortcomings, and the introduction of biological therapy changed the way physicians treat Crohn's disease ...