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It originally contained sodium bromide and acetanilide, both toxic substances which were eventually removed. Its current formulation contains the pain reliever aspirin and two reactive chemicals – sodium bicarbonate and citric acid – which creates effervescence when mixed with water. Sodium bicarbonate is an antacid.
ATC code A02 Drugs for acid related disorders is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Alka-Seltzer is a combination of sodium bicarbonate, aspirin, and anhydrous citric acid used for the relief of heartburn, acid indigestion, and stomach aches. [7] Alka-Seltzer is sold in foil packets, each containing two tablets. Prior to 1984, it was also available stacked in cylindrical glass bottles. It is available in many different flavors.
Andrews Liver Salts was a laxative and antacid for mild stomach complaints. It was sold as a powder which is added to water and mixed, creating effervescence, before being swallowed. The powder contains sugar; an antacid, sodium bicarbonate (22.6% w/w); citric acid (to provide effervescence) (19.5% w/w); and a laxative, magnesium sulphate (17.4
Almasilate is an antacid. It is available in Japan as a mixture with calcium carbonate, and sodium bicarbonate as a non-prescription medication. [ 1 ] It is also sold in Taiwan, Germany, and Spain.
Eno was first marketed by James Crossley Eno (1827–1915). [4] Legend has it that his idea for the product arose while he was working at the pharmacy of an infirmary in Newcastle, Britain, with Dennis Embleton; Embleton often prescribed an effervescent drink made by mixing sodium bicarbonate and citric acid in water, and Eno adopted this beverage. [5]
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Antacids are mainly classified into two categories: Systemic (absorbable) antacids: They are water soluble and systemically absorbed and pass into the bloodstream. e.g. sodium bicarbonate or sodium citrate; Non-systemic (non-absorbable) antacids: They are insoluble and not absorbed into systemic circulation.
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