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Tapentadol, sold under the brand names Nucynta and Palexia among others, is a synthetic opioid analgesic of the benzenoid class with a dual mode of action as a highly selective full agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI). [7]
Minecraft Dungeons is a 2020 dungeon crawler video game developed by Mojang Studios and Double Eleven and published by Xbox Game Studios. It is a spin-off of the sandbox video game Minecraft and was released for Nintendo Switch, PlayStation 4, Windows, and Xbox One in May 2020. It was also adapted into an arcade video game by Raw Thrills. The ...
Minecraft Legends is a 2023 real-time action-strategy [1] [2] [3] video game developed by Mojang Studios and Blackbird Interactive and published by Xbox Game Studios. A spin-off of the 2011 sandbox game Minecraft , it was released on Windows , Nintendo Switch , PlayStation 4 , PlayStation 5 , Xbox One , and Xbox Series X/S on April 18, 2023.
Greenfield is a fictional city created in the sandbox video game Minecraft. As of May 2022, the city is one-fourth complete and has a size of 20 million blocks. [2] The city was started by Minecraft user THEJESTR in August 2011. [3] [4] As of April 2022, there are approximately 1.3 million downloads of the city map. [5]
Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.
William Orville "Lefty" Frizzell (March 31, 1928 – July 19, 1975) was an American country and honky-tonk singer-songwriter. [1]Frizell is known as one of the most influential country music vocal stylists of all time.
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [6] [9] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [9]
According to a 2015 analysis, albiglutide is less effective than other GLP-1 agonists for lowering glycated hemoglobin (HbA 1c, an indicator for long-term blood glucose control) and weight loss. It also seems to have fewer side effects than most other drugs of this class, except for reactions at the injection site which are more common under ...