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The first example of an artificial molecular machine (AMM) was reported in 1994, featuring a rotaxane with a ring and two different possible binding sites. In 2016 the Nobel Prize in Chemistry was awarded to Jean-Pierre Sauvage, Sir J. Fraser Stoddart, and Bernard L. Feringa for the design and synthesis of molecular machines.
A photoswitch is a type of molecule that can change its structural geometry and chemical properties upon irradiation with electromagnetic radiation.Although often used interchangeably with the term molecular machine, a switch does not perform work upon a change in its shape whereas a machine does. [1]
Molecular motors are natural (biological) or artificial molecular machines that are the essential agents of movement in living organisms. In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work ; for example, many protein -based molecular motors harness the chemical free energy ...
Synthetic molecular motors are molecular machines capable of continuous directional rotation under an energy input. [2] Although the term "molecular motor" has traditionally referred to a naturally occurring protein that induces motion (via protein dynamics), some groups also use the term when referring to non-biological, non-peptide synthetic motors.
Molecular machines a molecule that mimics the function of macroscopic machines. Subcategories. This category has only the following subcategory. M. Motor proteins (36 P)
The activation strain model was originally proposed and has been extensively developed by Bickelhaupt and coworkers. [4] This model breaks the potential energy curve as a function of reaction coordinate, ζ, of a reaction into 2 components as shown in equation 1: the energy due to straining the original reactant molecules (∆E strain) and the energy due to interaction between reactant ...
The research group of John E. Walker, then at the MRC Laboratory of Molecular Biology in Cambridge, crystallized the F 1 catalytic-domain of ATP synthase. The structure, at the time the largest asymmetric protein structure known, indicated that Boyer's rotary-catalysis model was, in essence, correct.
A molecular assembler is a kind of molecular machine. Some biological molecules such as ribosomes fit this definition. This is because they receive instructions from messenger RNA and then assemble specific sequences of amino acids to construct protein molecules. However, the term "molecular assembler" usually refers to theoretical human-made ...