Ad
related to: estrogen receptor alpha antibody definition anatomy and physiology youtubelsbio.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein [5]) that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ESR1 (EStrogen Receptor 1). [6] [7] [8]
2101 26379 Ensembl ENSG00000173153 ENSMUSG00000024955 UniProt P11474 O08580 RefSeq (mRNA) NM_001282450 NM_001282451 NM_004451 NM_007953 RefSeq (protein) NP_001269379 NP_001269380 NP_004442 NP_031979 Location (UCSC) Chr 11: 64.31 – 64.32 Mb Chr 19: 6.89 – 6.9 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Estrogen-related receptor alpha (ERRα), also known as NR3B1 (nuclear ...
The first includes the intracellular estrogen receptors, namely ERα and ERβ, which belong to the nuclear receptor family. The second class consists of membrane estrogen receptors (mERs), such as GPER (GPR30), ER-X, and G q-mER, which are primarily G protein-coupled receptors. This article focuses on the nuclear estrogen receptors (ERα and ERβ).
The ERRs are orphan nuclear receptors, meaning the identity of their endogenous ligand has yet to be unambiguously determined. They are named because of sequence homology with estrogen receptors, but do not appear to bind estrogens or other tested steroid hormones. There are three human estrogen related receptors: ERRα ; ERRβ ; ERRγ
Estrogen insensitivity syndrome (EIS), or estrogen resistance, is a form of congenital estrogen deficiency or hypoestrogenism [2] which is caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological effects in the body. [3]
Typically, the antibody used is the anti-Estrogen Receptor (ER) (SP1) Rabbit Monoclonal Antibody. Employing SP1 allows detection of estrogen receptor (ER) antigens in sections of the fixed tissue samples. In conjunction with light microscopy, approximate ER activity can be estimated using the level of staining of the cell's components.
Estradiol affects target tissues mainly by interacting with two nuclear receptors called estrogen receptor α (ERα) and estrogen receptor β (ERβ). [ 36 ] [ 37 ] One of the functions of these estrogen receptors is the modulation of gene expression .
Estrogen is a lipid hormone in humans can regulate many physiological processes. [1] It is largely related to menstrual and estrous and its biological function is mediated by binding to two receptors: Estrogen Receptor alpha (ERα) and Estrogen Receptor beta (ERβ).
Ad
related to: estrogen receptor alpha antibody definition anatomy and physiology youtubelsbio.com has been visited by 10K+ users in the past month