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This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
It has also been investigated in the treatment of schizophrenia, [9] Parkinson's disease, and other dementia-related disorders. [ 10 ] Isocarboxazid, as well as other MAOIs, increase the levels of the monoamine neurotransmitters serotonin , dopamine , norepinephrine , epinephrine , melatonin , and phenethylamine in the brain.
Antidepressants are recommended as an alternative or additional first step to self-help programs in the treatment of bulimia nervosa. [37] SSRIs (fluoxetine in particular) are preferred over other anti-depressants due to their acceptability, tolerability, and superior reduction of symptoms in short-term trials.
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [6] [9] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [9]
The guidelines recommended that antidepressant treatment be considered: For people with a history of moderate or severe depression. For people with mild depression that has been present for an extended period. As a first-line treatment for moderate to severe depression.
Newer MAOIs such as selegiline (typically used in the treatment of Parkinson's disease) and the reversible MAOI moclobemide provide a safer alternative [19] and are now sometimes used as first-line therapy. Pargyline is a non-selective MAOI that was previously used as an antihypertensive agent to treat hypertension (high blood pressure). [21] [22]
Psychotherapy is the treatment of choice in those under the age of 18, with medication offered only in conjunction with the former and generally not as a first line agent. The possibility of depression, substance misuse or other mental health problems in the parents should be considered and, if present and if it may help the child, the parent ...
It thus did not recommend duloxetine as a first-line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. [25] Duloxetine appears less tolerable than some other antidepressants. [26] Generic duloxetine became available in 2013. [27]
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