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The aminosalicylates used to treat ulcerative colitis include the following: Mesalazine, also known as 5-aminosalicylic acid, mesalamine, or 5-ASA. Brand names include: Asacol, Octasa, Pentasa, Salofalk, Lialda, Ipocol, Apriso, and Mezavant. Sulfasalazine, also known as Azulfidine. This drug is in a traditional class of antibiotics, but ...
Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, also sends Crohn's disease into clinical remission, new findings suggest.
On Wednesday, the FDA approved Eli Lilly And Co’s (NYSE:LLY) Omvoh (mirikizumab-mrkz) for moderately to severely active Crohn’s disease in adults. Omvoh is now approved in the U.S. for two ...
Sulfasalazine, sold under the brand name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. [5] It is considered by some to be a first-line treatment in rheumatoid arthritis. [6] It is taken by mouth or can be administered rectally. [5]
Ozanimod, sold under the brand name Zeposia, is an immunomodulatory medication for the treatment of relapsing multiple sclerosis and ulcerative colitis. [3] [4] [6] [7] It acts as a sphingosine-1-phosphate receptor (S1PR) agonist, sequestering lymphocytes to peripheral lymphoid organs and away from their sites of chronic inflammation.
Mirikizumab was developed by Eli Lilly and Company. [11]The approval was based on the LUCENT 1 clinical study which evaluated the safety and efficacy of mirikizumab in participants with moderately to severely active ulcerative colitis (UC) who have had an inadequate response to, loss of response, or intolerant to conventional or biologic therapy for UC.
The drug, etrasimod, was the key asset Pfizer picked up in its $6.7 billion deal for Arena Pharmaceuticals last year. Ulcerative colitis (UC) is an inflammatory bowel disease.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
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