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There were outbreaks of dog food containing aflatoxin in North America in late 2005 and early 2006, [38] and again in late 2011. [39] Mycotoxins in animal fodder, particularly silage, can decrease the performance of farm animals and potentially kill them. [40] [4] Several mycotoxins reduce milk yield when ingested by dairy cattle. [40]
Biosynthesis pathway of fumitremorgin pathway involves several different enzymes. FtmA is a nonribosomal peptide synthase. Both FtmB and FtmH are prenyltransferase.Three different cytochrome P450 monooxygenases involved in the biosynthesis of furmitremorgin C are FtmC, FtmE, and FtmG.
Some articles have suggested the toxic level in dog food is 100–300 ppb and requires continuous exposure or consumption for a few weeks to months to develop aflatoxicosis. [39] No information is available to suggest that recovered dogs will later succumb to an aflatoxin-induced disease. Turkeys are extremely susceptible to aflatoxicosis.
This disease was the turning point for the use of the term mycotoxin. In the 1960s, about 100,000 turkey poults died near London, England due to peanut meal that was contaminated by Mycotoxins produced by Aspergillus flavus. Studies showed that the age group that was most affected was turkeys from two to twenty weeks old.
Aspergillus ochraceus is a mold species in the genus Aspergillus known to produce the toxin ochratoxin A, one of the most abundant food-contaminating mycotoxins, and citrinin. It also produces the dihydroisocoumarin mellein. It is a filamentous fungus in nature and has characteristic biseriate conidiophores.
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Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, [1] as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.
Zearalenone is a white crystalline solid, with molecular formula C 18 H 22 O 5 and 318.364 g/mol molecular weight. It is a resorcyclic acid lactone.It exhibits blue-green fluorescence when excited by long wavelength ultraviolet (UV) light (360 nm) and a more intense green fluorescence when excited with short wavelength UV light (260 nm). [4]
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