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  2. Experimental treatment pushed by ALS patients gets day ... - AOL

    www.aol.com/news/experimental-treatment-pushed...

    NurOwn is the clearest test yet of how far the agency may be willing to bend to approve a new medicine for a rare and deadly condition with few treatment options. ALS gradually destroys nerve ...

  3. New treatment may slow ALS, with help from Ice Bucket ... - AOL

    www.aol.com/treatment-may-slow-als-help...

    An experimental medication may slow the progression of amyotrophic lateral sclerosis, or ALS, researchers reported Wednesday. The research was supported in part by donations from the Ice Bucket ...

  4. Denali-Sanofi's ALS drug fails to meet mid-stage trial goal - AOL

    www.aol.com/news/denali-sanofis-als-drug-fails...

    Shares of Denali were down nearly 8% in morning trading. This marks the latest setback in the long list of roadblocks in the path to develop effective treatments against amyotrophic lateral ...

  5. ALS Therapy Development Institute - Wikipedia

    en.wikipedia.org/wiki/ALS_Therapy_Development...

    The institute has raised and spent more than $100 million on research into effective treatments for ALS and practices open-source science. [19] After the discovery that the multiple sclerosis drug Gilenya might also be a treatment for ALS, the Institute enrolled 30 people in a Phase 2A clinical trial the drug in 2013, though it did not progress further.

  6. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    The lifetime risk of developing ALS is 1:350 for European men and 1:400 for European women. Men have a higher risk mainly because spinal-onset ALS is more common in men than women. [63] The number of those with ALS in the United States in 2015 was 5.2 people per 100,000, and was higher in whites, males, and people over 60 years old. [124]

  7. Riluzole - Wikipedia

    en.wikipedia.org/wiki/Riluzole

    Riluzole is a medication used to treat amyotrophic lateral sclerosis (ALS) and other motor neuron diseases. Riluzole delays the onset of ventilator-dependence or tracheostomy in some people and may increase survival by two to three months. [5] Riluzole is available in tablet and liquid form.

  8. ALS drug will be pulled from US market after study showed ...

    www.aol.com/news/als-drug-pulled-us-market...

    The maker of a drug for Lou Gehrig’s disease that recently failed in a large study said Thursday it will pull the medicine from the market, acknowledging it didn't help patients with the deadly ...

  9. Tofersen - Wikipedia

    en.wikipedia.org/wiki/Tofersen

    Tofersen was developed by Ionis Pharmaceuticals and was licensed to, and co-developed by, Biogen. [7] [8]The effectiveness of tofersen was evaluated in a 28-week, randomized, double-blind, placebo-controlled clinical study in 147 participants with weakness attributable to amyotrophic lateral sclerosis and a superoxide dismutase 1 (SOD-1) mutation confirmed by a central laboratory. [2]

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