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2. Multiple sclerosis - Wikipedia

   en.wikipedia.org/wiki/Multiple_sclerosis

   Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

3. Lesional demyelinations of the central nervous system

   en.wikipedia.org/wiki/Lesional_demyelinations_of...

   Standard multiple sclerosis, the most known and extended variant. Devic's disease and neuromyelitis optica (NMO) (sometimes previously called optic-spinal MS) Acute disseminated encephalomyelitis or ADEM, a closely related disorder in which a known virus or vaccine triggers autoimmunity against myelin.

4. Pathology of multiple sclerosis - Wikipedia

   en.wikipedia.org/.../Pathology_of_multiple_sclerosis

   It also seems that myelin basic protein (MBP) from multiple sclerosis (MS) patients contains lower levels of phosphorylation at Thr97 than normal individuals. [152] NAWM is the place where lesions appear and the process seems to be made by microglia, in absence of leukocyte infiltration, astrogliosis or demyelination.

5. Inflammatory demyelinating diseases of the central nervous ...

   en.wikipedia.org/wiki/Inflammatory_demyelinating...

   Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.

6. Demyelinating disease - Wikipedia

   en.wikipedia.org/wiki/Demyelinating_disease

   In the second group, the myelin is inherently abnormal and undergoes degeneration. [6] The Poser criteria named this second group dysmyelinating diseases. [7] In the most well-known demyelinating disease, multiple sclerosis, evidence suggests that the body's immune system plays a significant role.

7. Myelin - Wikipedia

   en.wikipedia.org/wiki/Myelin

   Demyelination is the loss of the myelin sheath insulating the nerves, and is the hallmark of some neurodegenerative autoimmune diseases, including multiple sclerosis, acute disseminated encephalomyelitis, neuromyelitis optica, transverse myelitis, chronic inflammatory demyelinating polyneuropathy, Guillain–Barré syndrome, central pontine ...