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Therefore, removal of the spleen runs the risk of overwhelming post-splenectomy infection, a medical emergency and rapidly fatal disease caused by the inability of the body's immune system to properly fight infection following splenectomy or asplenia. [1] Common indications for splenectomy include trauma, tumors, splenomegaly or for ...
An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis , and are caused by encapsulated organisms including Streptococcus pneumoniae . [ 3 ]
Splenic infarct seen on CT Healed splenic infarct. Several factors may increase the tendency for clot formation, such as specific infections (such as infectious mononucleosis, [9] [dubious – discuss] [better source needed] cytomegalovirus infection, [10] malaria, [11] or babesiosis [12]), inherited clotting disorders (thrombophilia, such as Factor V Leiden, antiphospholipid syndrome ...
Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease
Splenic artery embolization is a minimally invasive procedure and, where successful, avoids splenectomy. If an individual's spleen is enlarged, as is frequent in mononucleosis , most physicians will advise against activities (such as contact sports ) where injury to the abdomen could be catastrophic.
Lack of a spleen, called asplenia, can occur by autosplenectomy or the surgical counterpart, splenectomy. Asplenia can increase susceptibility to infection. [3] Autosplenectomy can occur in cases of sickle-cell disease where the misshapen cells block blood flow to the spleen, causing scarring and eventual atrophy of the organ. [2]
The original procedure also consisted of an esophageal transection, splenectomy, vagotomy, and pyloroplasty. [ citation needed ] The Sugiura procedure was originally associated with significant morbidity and mortality ; in recent years, though, this procedure and its modifications have been performed in many hepatobiliary and pancreatic ...
This abscess develops after surgical operations like splenectomy. Presents with cough, increased respiratory rate with shallow respiration, diminished or absent breath sounds, hiccups, dullness in percussion, tenderness over the 8th–11th ribs, fever, chills, anorexia and shoulder tip pain on the affected side.