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The postcoital test (PCT), also known as the Sims test, Hühner test ,Sims–Hühner test, or cervical mucous penetration assay is a test in the evaluation of infertility. The test examines interaction between sperm and mucus of the cervix .
The sperm–cervical mucus contact test is an in-vitro slide test used for detecting antispermal antibodies. [1] It is one of the investigations done for infertility. It should not be confused with Kurzrock–Miller test , where there is interface between the two materials; whereas in this test the materials are thoroughly mixed.
In March 2016, Labcorp acquired Pathology Inc., a provider of reproductive donor testing as well as anatomic, molecular and digital pathology services focused on women's health. [55] In September 2016, Labcorp acquired Sequenom for $371 million including debt, expanding its operations in Europe and Asia. [56] [57]
Sperm Chromatin Structure Assay (SCSA) is a diagnostic approach that detects sperm abnormality with a large extent of DNA fragmentation. [1] First described by Evenson in 1980, the assay is a flow cytometric test that detects the vulnerability of sperm DNA to acid-induced denaturation DNA in situ. [2]
The most common reasons for laboratory semen analysis in humans are as part of a couple's infertility investigation and after a vasectomy to verify that the procedure was successful. [4] It is also commonly used for testing human donors for sperm donation, and for animals semen analysis is commonly used in stud farming and farm animal breeding.
Molecular diagnostics DNA testing may be done here, along with a subspecialty known as cytogenetics. [10] Reproductive biology testing is available in some laboratories, including Semen analysis, Sperm bank and assisted reproductive technology. Layouts of clinical laboratories in health institutions vary greatly from one facility to another.
However, only Mixed Antiglobulin Reaction (MAR) test and Immunobead Test (IBT) are currently being recommended by the WHO for the assessment of human sperm antibodies. [ 10 ] MAR test in its original version is based on the classical Coombs test ; sperm is mixed with human red blood cells coated with human IgG.
A semen analysis typically measures the number of sperm per millilitre of ejaculate, and analyzes the morphology (shape) and motility (ability to swim forward) of the sperm (the typical ejaculate of a healthy, physically mature young adult male of reproductive age with no fertility-related problems usually contains 300–500 million spermatozoa ...