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Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (JRA), [1] is the most common chronic rheumatic disease of childhood, affecting approximately 3.8 to 400 out of 100,000 children. [3] Juvenile, in this context, refers to disease onset before 16 years of age, while idiopathic refers to a condition with no ...
Researchers have found that there is an elevation of cytokines like IL-1 and IL-18 in individuals with systemic juvenile idiopathic arthritis. [17] In juvenile idiopathic arthritis (JIA) individuals, it is theorized that a possible environmental trigger for this condition is an infection due to the discovery of elevated heat shock proteins in ...
The most common rheumatic diseases are osteoarthritis, rheumatoid arthritis, lupus, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis, fibromyalgia, and gout. Osteoarthritis
Systemic-onset juvenile idiopathic arthritis (sJIA), also known as Still disease, Still's disease, and systemic juvenile idiopathic arthritis, is a subtype of juvenile idiopathic arthritis (JIA) that is distinguished by arthritis, a characteristic erythematous skin rash, and remitting fever. [5] Fever is a common symptom in patients with sJIA ...
Uveitis. Uveitis (/ ˌjuːvi.aɪtɪs /) is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. [1] The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid.
Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [ 5 ] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [ 2 ] With AS, eye and bowel problems—as well as back pain—may occur. [ 2 ]
Arthritis is a term often used to mean any disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2] [3] In some types of arthritis, other organs are also affected. [7] Onset can be gradual or sudden. [6]
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis, where medium-sized blood vessels become inflamed throughout the body. [1]