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2. Equianalgesic - Wikipedia

   en.wikipedia.org/wiki/Equianalgesic

   Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

3. Sertraline - Wikipedia

   en.wikipedia.org/wiki/Sertraline

   Bioavailability is likely linear and dose-proportional over a dose range of 150 to 200 mg. [5] Concomitant intake of sertraline with food slightly increases sertraline peak levels and total exposure. [5] There is an approximate 2-fold accumulation of sertraline with continuous administration and steady-state levels are reached within one week. [5]

4. Threshold dose - Wikipedia

   en.wikipedia.org/wiki/Threshold_dose

   Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]

5. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

   www.aol.com/switching-antidepressants-safety...

   Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. Effectiveness and side effect rates can vary ...

6. List of psychotropic medications - Wikipedia

   en.wikipedia.org/wiki/List_of_psychotropic...

   Zoloft – an antidepressant of the SSRI class; Zonegran (zonisamide) – an anticonvulsant used to treat other seizures; Zulresso (brexanolone) – a GABA modulator antidepressant; Zyban (bupropion) – same active ingredient as Wellbutrin, but marketed as a smoking cessation aid

7. Can Zoloft & Other SSRIs Cause "Intimate" Side Effects?

   www.aol.com/zoloft-other-ssris-cause-intimate...

   Adjusting your dosage of Zoloft. Zoloft is prescribed at several dosages, from 25mg to 200mg per day. Some side effects, including intimate effects, may be more common when Zoloft is used at a ...

8. Selective serotonin reuptake inhibitor - Wikipedia

   en.wikipedia.org/wiki/Selective_serotonin...

   They showed that "In terms of efficacy, all antidepressants were more effective than placebo, with odds ratios (ORs) ranging between 2.13 (95% credible interval [CrI] 1.89–2.41) for amitriptyline and 1.37 (1.16–1.63) for reboxetine." [16] The odds ratios were specifically in terms of response rates (≥50% reduction in observer-rated ...

9. Drug titration - Wikipedia

   en.wikipedia.org/wiki/Drug_titration

   Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [1] When a drug has a narrow therapeutic index, titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [2]