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FATE syndrome develops in approximately 70% of cases as a result of heart disease, most commonly heart disease with cardiac wall thickening (Hypertrophic Cardiomyopathy, HCM). Up to 17% of cats with HCM experience arterial thromboembolism, but cats with other cardiomyopathies are also at increased risk.
Feline hypertrophic cardiomyopathy (HCM) is the most common heart disease in domestic cats; [69] [70] [71] the disease process and genetics are believed to be similar to the disease in humans. [72] In Maine Coon cats, HCM has been confirmed as an autosomal dominant inherited trait. [73] Numerous cat breeds have HCM as a problem in the breed. [74]
Feline disease refers to infections or illnesses that affect cats. They may cause symptoms, sickness or the death of the animal. Some diseases are symptomatic in one cat but asymptomatic in others. Feline diseases are often opportunistic and tend to be more serious in cats that already have concurrent sicknesses.
Hypertrophic cardiomyopathy screening is an assessment and testing to detect hypertrophic cardiomyopathy (HCM). [ 1 ] [ 2 ] It is a way of identifying HCM in immediate relatives of family members diagnosed with HCM, and athletes as part of a sports medical . [ 3 ]
Domestic cats are affected by over 250 naturally occurring hereditary disorders, many of which are similar to those in humans, such as diabetes, hemophilia and Tay–Sachs disease. [ 3 ] [ 5 ] For example, Abyssinian cat 's pedigree contains a genetic mutation that causes retinitis pigmentosa , which also affects humans.
It is a diagnosis of exclusion which means other possible urinary diseases which could cause bladder inflammation (e.g. feline urinary tract infections or urolithiasis) are ruled out. [5] Research is still being pursued regarding the causes of cystitis in cats, though the following principal risk factors have been identified: [14]
Hypertrophic cardiomyopathy is a disease in which the heart muscle (myocardium) becomes abnormally thick (hypertrophied). A thick heart muscle makes it difficult for the cat's heart to pump blood. [28] HCM is a common genetic disease in Bengal cats and there is no genetic testing available as of 2018.
The erythrocytic disease is not as important for clinical disease, but is often used to diagnose C. felis because piroplasms (erythrocytes that have phagocytized merozoites) can be seen on a peripheral blood smear under the microscope. [4] It is not clear why some cats become clinically affected with C. felis while others